Pipeline

Through joint collaborations with top pharmaceutical companies and research institutions, KREX has been used to identify autoantibody biomarkers for commercial precision immuno-profiling and screening applications. In addition, KREX has also been used to identify biologics with therapeutic potential.

Stage

Project

Pilot

Candidate id

Validation

Clinical Trial

Commercialisation

Companion Diagnostics

Cancer Immunotherapy PD1 inhibitor
Autoimmune Disease Drug 1
Autoimmune Disease Drug 2

Disease Precision
Immuno-Profiling

Melanoma
NSCLC
Gastric Cancer
Breast Cancer

Therapeutic Autoantibodies

Rheumatoid Arthritis - A
Autism
Lupus
Parkinson's
Aging
Rheumatoid Arthritis - B

FEATURED PRODUCTS

High-throughput autoantibody profiling against 1600+ proteins

Quantification of autoantibodies to 200+ clinically relevant CT antigens

Simultaneous screening of 100+
wild-type and mutant p53

Multi-antigen, multi-domain
COVID-19 antibody test

Sengenics - Functional Proteomics | Krex Technology | Protein Microarray Supplier

Sengenics is a Functional Proteomics company that leverages its patented KREX technology to discover autoantibody biomarker signatures for prediction of drug response and severe immune-related adverse events (irAEs). KREX can also be used to identify autoantibody biomarkers to diagnose cancer, autoimmune, neurodegenerative or infectious diseases with higher sensitivity and specificity than conventional diagnostic tests. Some autoantibodies that are identified as diagnostic biomarkers may be protective and have potential in themselves as therapeutic biomolecules.

Copyright 2008 – 2021 Sengenics All rights reserved | Sengenics Corporation LLC. Registered in Delaware, USA no. 5739583 | Sengenics UK Registered in England and Wales no. 12889389

X