Products & Services

Sengenics AxCESS Protein Arrays

The Sengenics AxCESS research service packages feature three KREX-based functional protein arrays developed for high-throughput and cost-effective immuno-proteomics applications. These protein arrays utilise the patented KREX protein folding technology for the production of full-length, correctly folded and functional proteins.

This range of arrays provide easy access to Sengenics’ KREX technology to enable high-specificity autoantibody characterisation with a focus on autoimmune, cancer and neurodegenerative disorders. All packages are carried out on a standard “fee-for-service” basis that include running of assays with integrated bioinformatics analysis and reporting.

Sengenics Immunome AxCESS Array

Contains over 1600 correctly folded and functional human proteins spotted in duplicate. Screen up to 2 samples per slide. Key applications include:

Sengenics CTA AxCESS Array

Contains over 200 correctly folded and functional CT antigens spotted in duplicate. Screen up to 8 samples per slide. Key applications include:

Sengenics OncoREX p53 Array

Contains over 100 correctly folded and functional wild type and mutant p53 spotted in duplicate. Screen up to 8 samples per slide. Key applications include:

Sengenics ImmuSAFE COVID+ Array

Measure three critical components of COVID-19 from a single sample on one chip:

  • Antibodies to N or S
  • Neutralising antibodies to S
  • Autoantibodies implicated in COVID-19 severity


Contains multiple SARS-CoV-2 specific domains (Nucleocapsid and Spike proteins) including full-length and numerous truncated versions and IFN, TNF, ANA etc. Key applications include:

Sengenics Joint Discovery Program

Sengenics is actively seeking collaborators for joint research and development programs in specific, market-addressable, cancer and autoimmune diseases. We also have a keen interest in Alzheimer’s and Parkinson’s research. Under our Discovery program, Sengenics offers its products and services under a collaborative framework encompassing sharing of IP and commercialisation rights.


We are also interested to hear from pharmaceutical, biopharmaceutical and biotech companies with an interest to discover, develop or license in diagnostic, drug response prediction or ADR/irAE prediction biomarker signatures.

Sengenics KREX Custom Array

  • High-throughput, fully customised content protein arrays targetted for validation studies, diagnostics or any bespoke application
 

Other Products

SEROMAX Blood Collection Kit

  • Safe and practical collection of samples for clinical trials, without requiring a cold chain, hence improving patient recruitment

SYMPHONI

  • Proprietary Sengenics database from 10,000s human autoantibody profiles
  • Improve specificity of identified biomarkers by cross referencing against Symphoni

FEATURED PRODUCTS

High-throughput autoantibody profiling against 1600+ proteins

Quantification of autoantibodies to 200+ clinically relevant CT antigens

Simultaneous screening of 100+
wild-type and mutant p53

Multi-antigen, multi-domain
COVID-19 antibody test

Sengenics - Functional Proteomics | Krex Technology | Protein Array Supplier

Sengenics is a Functional Proteomics company that leverages its patented KREX technology to discover autoantibody biomarker signatures for prediction of drug response and severe immune-related adverse events (irAEs). KREX can also be used to identify autoantibody biomarkers to diagnose cancer, autoimmune, neurodegenerative or infectious diseases with higher sensitivity and specificity than conventional diagnostic tests. Some autoantibodies that are identified as diagnostic biomarkers may be protective and have potential in themselves as therapeutic biomolecules.

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