Reliable biomarkers are essential tools for tracking disease course, assessing stage, and predicting progression. They are especially critical for guiding treatment decisions when the risk of severe side effects is high.

Autoantibody biomarkers can reveal predictive signatures, helping identify patients who are likely to respond to treatment—and those who may experience adverse reactions. These insights enable more personalized and safer therapeutic approaches.

Our advanced assays allow for the simultaneous analysis of numerous autoantibody targets, accelerating the discovery and validation of biomarkers with high predictive value. This capability brings us closer to a future of precise, individualized patient care.

Accelerating Discovery of Autoantibody Signatures

Sengenics provides powerful solutions for discovering biomarker signatures that can help predict disease progression and treatment outcomes. Our high-density protein microarray assays enable precise, reproducible detection of autoantibodies directly from patient serum, identifying disease-associated protein antigens, pathogenic antibodies, and protective antibodies to drive advances in precision medicine.

Related Study

Predictive Autoantibody Biomarker Panel in NSCLC

Kaplan Meier curve showing overall survival of patients with high and low expression of a 13-autoantibody biomarker signature in non-small cell lung cancer (NSCLC) patients who have undergone lung resection.  Poor survivor ship is demonstrated in patient with high expression of the signature with an overall 5-year survival rate of 7.6%.​

Source: Patel, A.J., et. al., A highly predictive autoantibody-based biomarker panel for prognosis in early-stage NSCLC with potential therapeutic implications, British Journal of Cancer (2021)​.

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