Autoimmune Disease
Cunningham, K.Y., Hur, B., Gupta, V.K. et al. "Patients with ACPA-positive and ACPA-negative rheumatoid arthritis show different serological autoantibody repertoires and autoantibody associations with disease activity." Sci Rep 13, 5360 (2023). https://doi.org/10.1038/s41598-023-32428-4 View Paper
Stensballe, Allan, Poulsen, Thomas B. G., et al. 2021. “Identification of Potential Autoantigens in Anti‑CCP‑positive and Anti‑CCP‑negative Rheumatoid Arthritis using Citrulline‑specific Protein Arrays.” Nature (2021) 11:17300 doi.org/10.1038/s41598-021-96675-z View Paper
Chen, Po-Ku, Joung-Liang Lan, Yi-Ming Chen, et al. 2021. “Anti-TROVE2 Antibody Determined by Immune-Related Array May Serve as a Predictive Marker for Adalimumab Immunogenicity and Effectiveness in RA.” Edited by Baohui Xu. Journal of Immunology Research 2021 (March): 1–13. doi:10.1155/2021/6656121 View Paper
Mak, Anselm, Nien Yee Kow, Nur Hafiza Ismail, et al. 2020. “Detection of Putative Autoantibodies in Systemic Lupus Erythematous Using a Novel Native-Conformation Protein Microarray Platform.” Lupus 29 (14): 1948–54. doi:10.1177/0961203320959696 View Paper
Identification of Novel Native Autoantigens in Rheumatoid Arthritis
Poulsen, Thomas B. G., Dres Damgaard, Malene Møller Jørgensen, et al. 2020. “Identification of Novel Native Autoantigens in Rheumatoid Arthritis.” Biomedicines 8 (6): 141. doi:10.3390/biomedicines8060141 View Paper
Autoantibodies Targeting TLR and SMAD Pathways Define New Subgroups in Systemic Lupus Erythematosus
Lewis, Myles J., Michael B. McAndrew, Colin Wheeler, et al. 2018. “Autoantibodies Targeting TLR and SMAD Pathways Define New Subgroups in Systemic Lupus Erythematosus.” Journal of Autoimmunity 91 (July): 1–12. doi:10.1016/j.jaut.2018.02.009 View Paper
Cancer
Akshay J. Patel, Ti-Myen Tan, Alex G. Richter, Babu Naidu, Jonathan M. Blackburn and Gary W. Middleton. 2021. “A Highly Predictive Autoantibody-based Biomarker Panel for Prognosis in Early-stage NSCLC with Potential Therapeutic Implications” British Journal of Cancer. doi: 10.1038/s41416-021-01572-x View Paper
B Cells and Antibody Production in Melanoma
Da Gama Duarte, Jessica, Janique M. Peyper, and Jonathan M. Blackburn. 2018. “B Cells and Antibody Production in Melanoma.” Mammalian Genome 29 (11): 790–805. doi:10.1007/s00335-018-9778-z View Paper
A Diagnostic Autoantibody Signature for Primary Cutaneous Melanoma
Zaenker, Pauline, Johnny Lo, Robert Pearce, et al. 2018. “A Diagnostic Autoantibody Signature for Primary Cutaneous Melanoma.” Oncotarget 9 (55): 30539–51. doi:10.18632/oncotarget.25669. View Paper
Da Gama Duarte, Jessica, Sagun Parakh, Miles C. Andrews, et al. 2018. “Autoantibodies May Predict Immune-Related Toxicity: Results from a Phase I Study of Intralesional Bacillus Calmette–Guérin Followed by Ipilimumab in Patients with Advanced Metastatic Melanoma.” Frontiers in Immunology 9. doi:10.3389/fimmu.2018.00411. View Paper
Adeola, Henry A., Muneerah Smith, Lisa Kaestner, et al. 2016. “Novel Potential Serological Prostate Cancer Biomarkers Using CT100+ Cancer Antigen Microarray Platform in a Multi-Cultural South African Cohort.” Oncotarget 7 (12): 13945–64. doi:10.18632/oncotarget.7359. View Paper
Beeton-Kempen, Natasha, Jessica Duarte, Aubrey Shoko, et al. 2014. “Development of a Novel, Quantitative Protein Microarray Platform for the Multiplexed Serological Analysis of Autoantibodies to Cancer-Testis Antigens.” International Journal of Cancer 135 (8): 1842–51. doi:10.1002/ijc.28832. View Paper
Serologic Autoantibodies as Diagnostic Cancer Biomarkers — A Review
Zaenker, Pauline, and Melanie R. Ziman. 2013. “Serologic Autoantibodies as Diagnostic Cancer Biomarkers—A Review.” Cancer Epidemiology and Prevention Biomarkers 22 (12): 2161–81. doi:10.1158/1055-9965.EPI-13-0621. View Paper
Duarte, Jessica, Jean-Michel Serufuri, Nicola Mulder, et al. 2013. “Protein Function Microarrays: Design, Use and Bioinformatic Analysis in Cancer Biomarker Discovery and Quantitation.” In Bioinformatics of Human Proteomics, edited by Xiangdong Wang, 39–74. Translational Bioinformatics. Dordrecht: Springer Netherlands. doi:10.1007/978-94-007-5811-7_3 View Paper
Gnjatic, Sacha, Colin Wheeler, Martin Ebner, et al. 2009. “Seromic Analysis of Antibody Responses in Non-Small Cell Lung Cancer Patients and Healthy Donors Using Conformational Protein Arrays.” Journal of Immunological Methods 341 (1–2): 50–58. doi:10.1016/j.jim.2008.10.016 View Paper
Functional Protein Microarrays for Parallel Characterisation of P53 Mutants
Boutell, Jonathan M., Darren J. Hart, Benjamin L. J. Godber, et al. 2004. “Functional Protein Microarrays for Parallel Characterisation of P53 Mutants.” PROTEOMICS 4 (7): 1950–58. doi:https://doi.org/10.1002/pmic.200300722 View Paper
Infectious Disease
Michelle O. Mullins, Muneerah Smith, Hazel Maboreke, Andrew J. M. Nel, Ntobeko A. B. Ntusi, Wendy A. Burgers and Jonathan M. Blackburn. 2023.Epitope Coverage of Anti-SARS-CoV-2 Nucleocapsid IgA and IgG Antibodies Correlates with Protection against Re-Infection by New Variants in Subsequent Waves of the COVID-19 Pandemic. Viruses 2023,15,584. https://doi.org/ 10.3390/v15020584 View Paper
Muneerah Smith, Gaurav Kwatra, Alane Izu, Andrew Nel, Clare Cutland, Khatja Ahmed, Vicky Baillie, Shaun Barnabas, Qasim Bhorat , Carmen Briner, Erica Lazarus, Keertan Dheda, Lee Fairlie, Anthonet Koen, Shabir Madhi and Jonathan M. Blackburn. 2023. Longitudinal IgA and IgG Response, and ACE2 Binding Blockade, to Full-Length SARS-CoV-2 Spike Protein View Paper
Age, Disease Severity and Ethnicity Influence Humoral Responses in a Multi-Ethnic COVID-19 Cohort
Smith, M.; Abdesselem, H.B.; Mullins, M.; Tan, T.-M.; Nel, A.J.M.; Al-Nesf, M.A.Y.; Bensmail, I.; Majbour, N.K.; Vaikath, N.N.; Naik, A.; et al. Age, Disease Severity and Ethnicity Influence Humoral Responses in a Multi-Ethnic COVID-19 Cohort. Viruses 2021, 13, 786. https://doi.org/10.3390/ v13050786 View Paper
Blackburn, Jonathan M, Nurdiana Anuar, Ti Myen Tan, et al. 2020. “Quantitative, Epitope-Specific, Serological Screening of COVID-19 Patients Using a Novel Multiplexed Array-Based Immunoassay Platform.” Preprint. Infectious Diseases (except HIV/AIDS). doi:10.1101/2020.09.25.20201269 View Paper
COVID-19 Antibody Testing: From Hype to Immunological Reality
Gray, C. M., J. Peter, M. Mendelson, et al. 2020. “COVID-19 Antibody Testing: From Hype to Immunological Reality.” South African Medical Journal 110 (9): 837–41 View Paper
Soe, Hui, Yean Yong, Mazen M. Al-Obaidi, et al. 2018. “Identifying Protein Biomarkers in Predicting Disease Severity of Dengue Virus Infection Using Immune-Related Protein Microarray.” Medicine 97 (5). doi:10.1097/MD.0000000000009713 View Paper
Autoantibody Profile of Patients Infected with Knowlesi Malaria
Liew, Jonathan, Amirah Amir, Yeng Chen, et al. 2015. “Autoantibody Profile of Patients Infected with Knowlesi Malaria.” Clinica Chimica Acta; International Journal of Clinical Chemistry 448 (August): 33–38. doi:10.1016/j.cca.2015.06.006 View Paper
Neurological Disease
Identification of Novel Candidate Autoantibodies in Alzheimer’s Disease
B. Z. Wang, F. Z. Zailan, et al. 2020. “Identification of Novel Candidate Autoantibodies in Alzheimer’s Disease.” European Journal of Neurology 2020, 27: 2292–2296. doi:10.1111/ene.14290 View Paper
Suwarnalata, Gunasekaran, Ai Huey Tan, Hidayah Isa, et al. 2016. “Augmentation of Autoantibodies by Helicobacter Pylori in Parkinson’s Disease Patients May Be Linked to Greater Severity.” PloS One 11 (4): e0153725. doi:10.1371/journal.pone.0153725 View Paper
Other Diseases
Peritoneal Autoantibody Profiling Identifies p53 as an Autoantibody Target in Endometriosis
Harden, S., Tan, T. Y., & Lee, Y. H. et al. 2023. "Peritoneal autoantibody profiling identifies p53 as an autoantibody target in endometriosis." Fertility and Sterility® 2023 0015-0282 Copyright ©2023 American Society for Reproductive Medicine. https://doi.org/10.1016/j.fertnstert.2023.02.025 View Paper
Novel Auto-antibodies in Idiopathic Small Fiber Neuropathy
Amanda CY Chan, Hiu Yi Wong, Yao Feng Chong, et al. 2021. “Novel Auto-antibodies in Idiopathic Small Fiber Neuropathy” Annals of Neurology doi: 10.1002/ana.26268 View Paper
Chen, Chang-Hua, Ing-Lin Chang, Shu-Hui Wang, et al. 2020. “Potential Novel Proteomic Biomarkers for Diagnosis of Vertebral Osteomyelitis Identified Using an Immunomics Protein Array Technique: Two Cases Reports.” Medicine 99 (43): e22852. doi:10.1097/MD.0000000000022852 View Paper
Sumera, Afshan, Nur Diana Anuar, Ammu Kutty Radhakrishnan, et al. 2020. “A Novel Method to Identify Autoantibodies against Putative Target Proteins in Serum from Beta-Thalassemia Major: A Pilot Study.” Biomedicines 8 (5): 97. doi:10.3390/biomedicines8050097 View Paper
Technology
Pro-MAP: A Robust Pipeline for the Pre-processing of Single Channel Protein Microarray Data
Metoboroghene Oluwaseyi Mowoe, Shaun Garnett, Katherine Lennard, Jade Talbot, Paul Townsend, Eduard Jonas and Jonathan Michael Blackburn. 2022. "Pro-MAP: A Robust Pipeline for the Pre-processing of Single Channel Protein Microarray Data." BMC Bioinformatics (2022) 23:534 https://doi.org/10.1186/s12859-022-05095-x View Paper
Autoantibody-Based Diagnostic Biomarkers: Technological Approaches to Discovery and Validation
Aziz, Farhanah, Muneera Smith, and Jonathan M Blackburn. 2019. “Autoantibody-Based Diagnostic Biomarkers: Technological Approaches to Discovery and Validation.” In Autoantibodies and Cytokines, edited by Wahid Ali Khan. IntechOpen. doi:10.5772/intechopen.75200 View Paper
Aziz, Farhanah et al. 2018. “Applications of Functional Protein Arrays for Detection and Development of Autoantibody-based Diagnostics and Therapeutics.” International Biopharmaceutical Industry 1 (2). https://www.biopharmaceuticalmedia.com/applications-of-functional-protein-arrays-for-detection-and-development-of-autoantibody-based-diagnostic-and-therapeutic/ View Paper
Advances in the Development of Human Protein Microarrays
Duarte, Jessica G., and Jonathan M. Blackburn. 2017. “Advances in the Development of Human Protein Microarrays.” Expert Review of Proteomics 14 (7): 627–41. doi:10.1080/14789450.2017.1347042 View Paper
Protein Function Microarrays for Customised Systems-Oriented Proteome Analysis
Blackburn, Jonathan M., and Aubrey Shoko. 2011. “Protein Function Microarrays for Customised Systems-Oriented Proteome Analysis.” Methods in Molecular Biology (Clifton, N.J.) 785: 305–30. doi:10.1007/978-1-61779-286-1_21 View Paper
Sacha Gnjatic, Colin Wheeler, Martin Ebner, Erika Ritter, Anne Murray, Nasser K.Altorki, Cathy A.Ferrara, Henry Hepburne-Scott, Sarah Joyce, Jens Koopman, Michael B.McAndrew, Nicholas Workman, Gerd Ritter, Rachel Fallon, Lloyd J.Old. 2009. “Seromic analysis of antibody responses in non-small cell lung cancer patients and healthy donors using conformational protein arrays.” Journal View Paper
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