Immunoprofiling

Gain Invaluable Insights into Health and Disease

Antibodies are direct manifestations of disease, often appearing before symptoms arise and remaining detectable throughout the course of illness. With Sengenics’s innovative protein microarrays, powered by proprietary KREX^® technology, antibodies are measured against tens to thousands of correctly folded protein antigens to enhance understanding of immune responses, identify disease subtypes, discover new biomarkers, and inform potential therapies.

Dual Isotype Analysis

An antibody’s isotype defines its role in the immune response. By measuring different isotypes, valuable information about patient immune status and disease mechanisms is revealed. Sengenics microarrays facilitate the simultaneous profiling of IgG and IgA or IgM, offering more comprehensive insights than single isotype analysis.

IgG

The most abundant isotype, playing crucial roles in immune activation, pathogen detection, anti-tumor response, and inflammation.

IgA

An isotype found in secretions and blood, participating in pathogen neutralization and inflammation inhibition.

IgM

An isotype produced during the primary immune response with high avidity and involved in complement activation.

Don’t see what you need? Learn about our Custom Protein Assays.

Featured Application

Infectious Disease →

Related Resources

Publication: Age, Disease Severity and Ethnicity Influence Humoral Responses in a Multi-Ethnic COVID-19 Cohort →

Video: ImmuSAFE COVID+ Biochip Test →

Video: ImmuSAFE COVID+ Biochip Test for Seroprevalence Studies →

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Sengenics, a functional proteomics company, is committed to advancing precision medicine by empowering researchers with biologically relevant and actionable immunoproteomic insights across a broad spectrum of diseases. At the heart of its mission, Sengenics offers advanced, high-throughput tools using proprietary technology to precisely detect autoantibody biomarkers and protein interactions for basic, translational, and clinical research. Its robust tools have been leveraged by top pharmaceutical companies and leading research institutions to enhance disease understanding and streamline the biomarker pipeline.

Design and development by RainCastle Communications.

Gain Invaluable Insights into Health and Disease

Dual Isotype Analysis

IgG

IgA

IgM

Don’t see what you need? Learn about our Custom Protein Assays.

Featured Application

Related Resources

Ready to accelerate your program?

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Autoantibody-Based Diagnostic Biomarkers: Technological Approaches to Discovery and Validation

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